Each year, PCORnet connects researchers with health data from everyday healthcare encounters with more than 50 million people nationwide through eight PCORnet® Clinical Research Networks (CRNs) and 78 partner organizations participating in PCORnet.
Access to broad data through PCORnet helps researchers design and implement large-scale, innovative, patient-centered health research.
The following data visualizations illustrate a snapshot of PCORnet data resources from January 1, 2025 – December 31, 2025, unless otherwise noted.
Total Number of unique patients: 53,658,361
Data from PCORnet resources represent encounters with a diverse patient population from across the U.S. and include a wide range of ages, races, and ethnicities for males and females. The data are from patients with at least 1 face-to-face encounter and a recorded diagnosis in 2025.
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Explore Population Insights
Data accessed through PCORnet include topical reports based on services performed by healthcare professionals in ambulatory care or outpatient settings.
Download the full 2025 PCORnet® CRNs Population Insights Report.
PCORnet is a large, distributed “network of networks” funded by PCORI to improve the nation’s capacity to efficiently conduct health research, particularly patient-centered CER.
At the time of this report, PCORnet® Network Partners include eight PCORnet® Clinical Research Networks (CRNs) with 78 partner sites in addition to Patient Partners and the Coordinating Center for PCORnet®. Collectively, these sites are connected to more than 50 million people in the United States and include large academic health systems, hospitals, federally qualified health centers, and community clinics.
For more information on the structure and governance of PCORnet, please see the PCORnet® Playbook.
This report describes the results of a data query of the patient population with at least 1 face-to-face encounter and a recorded diagnosis code (e.g., ICD-10) at a health care setting across PCORnet between January 1 – December 31, 2025. The query results will enhance public awareness of the population of patients across sites participating in PCORnet that potentially would be available for future health care research.
Your research can go further, faster with PCORnet. Start the conversation about how the network can support your research at the PCORnet® Front Door.