Studies
Research projects designated as a PCORnet® Study represent a deeper level of partnership than standard Network use. PCORnet® Studies help strengthen the Network and drive patient-centered research while providing research teams with valuable benefits.
PCORnet® Studies are national in scope,
- include patient engagement throughout the project lifecycle,
- are committed to broad dissemination of findings,
- leverage PCORnet resources to improve the efficiency of patient-centered research (e.g., the PCORnet® Common Data Model (CDM), single IRB, engagement resources, data sharing agreements, etc.), and
- help build learning systems by sharing progress and lessons learned.
Research Made Easier
Learn about resources offered to researchers interested in using the PCORnet infrastructure.
PCORnet® Study Tracker
Review the PCORnet® Study Tracker
Effective March 2024
Search all PCORnet® Studies below, filtering by Status, Population or Therapeutic Area, or search by keyword.
- All ()
- Active, not recruiting ()
- Completed ()
- Enrolling by Invitation ()
- Not yet recruiting ()
- Recruiting ()
- Unknown Status ()
- All ()
- up to 21 Days (Child) ()
- up to 11 Years (Child) ()
- up to 21 Years (Child, Adult) ()
- up to 25 Years (Child, Adult) ()
- up to 79 Years (Child, Adult, Older Adult) ()
- 1 Year to 17 Years (Child) ()
- 5 to 19 Years and Adults 20+ Years (Child, Adult) ()
- 8 Years to 21 Years (Child, Adult) ()
- 18 Years and older (Adult, Older Adult) ()
- 18 Years to 75 Years (Adult, Older Adult) ()
- 19 Years and older (Adult, Older Adult) ()
- 30 Years and older (Adult, Older Adult) ()
- 40 Years to 80 Years (Adult, Older Adult) ()
- 75 Years and older (Older Adult) ()
- Adults with BMI 35+ who have had bariatric procedures ()
- All ()
- Auto Immune ()
- Cardiovascular ()
- Gastroenterology ()
- Health Disparities ()
- Infectious Disease ()
- Mental and Behavioral Health ()
- Metabolic Disorders ()
- Neurosciences ()
- Oncology ()
- Other, Data Quality Standards ()
- Other, Engagement ()
- Pulmonary ()
- Rare Disease ()
- Renal ()
Research Question(s): Can improved coordination of care between inpatient and outpatient teams working with ASCVD patients help prevent another cardiovascular event within one year in this high-r...
Research Question(s): Through this proposal, the research team will develop and test a new Co-creation in PCOR engagement measure that can be used to evaluate how researchers and community member...
Research Question(s): In this study, the research team wanted to learn if taking HCQ was safe and prevented COVID-19 in healthcare workers.
Research Question(s): The study will answer important questions patients are asking about the link between diabetes and COVID-19. To what extent does COVID-19 cause worse glycemic control, vas...
Research Question(s): Did a community rise in COVID-19 hospitalizations and deaths contribute to an increase in the risk of overdose among PCORnet patients? What role did public health and ...
Research Question(s): Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease, affecting over 3 million individuals worldwide and causing progressive lung function deteriorati...
Research Question(s): Can inclisiran be an effective solution to improve low-density lipoprotein-cholesterol management and close care gaps in an inclusive Atherosclerotic Cardiovascular Disease (...
Measurement Matters: Refining and Validating a Patient-Centered Outcomes Research Engagement Measure
Research Question(s): Can we develop a concise way to measure the extent to which researchers engaging older adults in research projects are doing so effectively and can we assign a score that...
Research Question(s): Does a text-messaging intervention improve healthy weight trajectories among children ages 0-2 compared to a health communication intervention delivered in pediatric primary ...
Research Question(s): How are patients' cancer screening practices impacted by bariatric surgery for weight loss?
Research Question(s): Can a research registry of people working in healthcare help to answer important questions about the COVID-19 pandemic on medications, vaccines and healthcare worker well-being?
Research Question(s): Can existing drugs be repurposed to treat Alzheimer's disease and related dementia?
Research Question(s): Can the use of EHR data develop predictive tools to assist healthcare providers in reaching earlier diagnoses and interventions, and improve the diagnostic journey and clinic...
Research Question(s): How does antibiotic use before age two affect weight and growth in children?
Research Question(s): We don’t know much about the long-term effectiveness of bariatric interventions. Can we use PCORnet to compare compare weight loss and safety among three popular bariatric ...
Research Question(s): Can remote blood pressure monitoring with cellular devices and tailored lifestyle coaching more effectively help reduce blood pressure and prevent secondary (another) str...
Research Question(s): Can we reduce the number of people who die from atherosclerotic cardiovascular disease (ASCVD) related deaths by using PCSK9 medicines to lower their cholesterol?
Research Question(s): What are the long term health effects of COVID-19 after a person has recovered from infection? How can we better detect, predict, treat these health effects and preven...
Research Question: Which dose of daily aspirin offers the right balance of effectiveness and minimal risk of bleeding? Can PCORnet be used to find the answer using a clinical trial model wherein pa...
Research Question(s): What is the occurrence of vascular, bleeding, or other events in Atrial Fibrillation or Atrial Flutter Patients patients?
Research Question(s): How well are clinics and patients controlling blood pressure, and would new programs or technologies help improve blood pressure control?
Research Question(s): What are the long term health effects of COVID-19 after a person has recovered from infection? How can we better detect, predict, and treat these health effects and pr...
Research Question(s): Which treatment options are most likely to improve important clinical outcomes in my child (or patient) with LGS? My child has hundreds of seizures a week, and multipl...
Research Question(s): Can we better understand why patients with type-2 diabetes may not receive guideline-recommended screening for diabetic kidney disease? Which medications may be most e...
Research Question(s): In patients with type 2 diabetes, are SGLT2 inhibitors or GLP-1 recent agonists better for preventing heart attack, stroke, blood vessel disease, heart failure, kidney di...
Research Question(s): Can we find ways to more accurately describe how suitable data are to answer a specific research question? What are the tools that can be used across studies to consis...
Research Question(s): How does receiving current recommended care affect long-term outcomes and healthcare needs amongst the numerous rare disease subtypes of congenital heart defects? What...
Research Question(s): What is the comparative impact of different shelter-in-place/reopening policies, overall and in vulnerable populations, on patient-reported financial insecurity, mental h...
Research Question(s): Which care options work, for whom, and under which circumstances in order to improve symptom management, treatment outcomes and quality of life among NET patients? Com...
Research Question(s): What is the comparative effectiveness of different payer or health system strategies that aim to prevent unsafe opioid prescribing while ensuring access to non-opioid metho...
Research Question(s): Can a research registry of patients with metastatic renal cell carcinoma (mRCC) patients help us better understand cancer management and health-related quality of life whil...
Research Question(s): How often is intensive behavioral therapy (IBT) being utilized in primary care and how has it impacted weight and diabetes outcomes for patients with and at-risk of type ...
Research Question(s): Can repurposed medications reduce symptoms of non-hospitalized participants with mild to moderate COVID-19?
Research Question(s): This trial will compare how patients with inactive spondyloarthritis on tumor necrosis factor inhibitor (TNFi) treatment respond to three treatment options that doctors cur...
Research Question(s): What are the differences in stone clearance and the lived experiences of youth, age 8-21 years, following ureteroscopy (URS), shock wave lithotripsy (SWL), and percutaneous n...
Research Question(s): Which blood pressure monitoring strategies, urine protein monitoring strategies, and blood pressure medication strategies are most effective in preserving kidney function i...
Research Question(s): How do patients with non-alcoholic steatohepatitis (NASH) or non-alcoholic fatty liver disease (NAFLD) compare with those who do not have these diagnoses? How is risk ...
Research Question(s): Can PCORnet be leveraged to implement patient-reported outcome measures in routine clinical practice for heart failure patients at three different institutions?
Research Question(s): What are the features of primary care telemedicine programs that have been newly implemented or expanded in response to the COVID-19 pandemic, and how do diverse populations ...
Research Question(s): Does mobile phone-delivered computerized cognitive behavioral therapy provide a greater benefit for daily pain and depression in adult patients with sickle cell disease than ...
Research Question(s): How do six classes of commonly prescribed medications influence weight, risk for diabetes, and cholesterol over time?
Research Question(s): Can a statin help prevent dementia and disability in adults aged 75 or older, as well as heart attacks and other cardiovascular-related deaths, while not increasing risks of ...