Study Updated 03/05/2024
ClinicalTrials.gov#: NCT02744846
Study Design: Retrospective Observational
PCORnet Infrastructure: Collaboration, CDM, Engagement
Principal Investigator: Jason Block
Site Name: Harvard Pilgrim Healthcare Institute
PCORnet® Network Partner: Legacy PCORnet Partner
Funder: Patient-Centered Outcomes Research Institute (PCORI); (Project webpage)
Funding Date: 2015
Study Duration: 2015 – 2018
Participating Clinical Research Networks: ADVANCE, GPC, INSIGHT, OneFlorida+, PEDSnet, REACHnet, STAR
Therapeutic Area: Metabolic Disorders
Population: up to 11 Years (Child)
Status: Completed
Research Question(s):
How does antibiotic use before age two affect weight and growth in children?
Primary Publication(s):
Early Antibiotic Exposure and Weight Outcomes in Young Children
Block JP, Bailey LC, Gillman M, et al. Early Antibiotic Exposure and Weight Outcomes in Young Children. Pediatrics, 2018; 142(6), p.e20180290.
Maternal antibiotic use during pregnancy and childhood obesity at age 5 years
Heerman WJ, Daley MF, Boone-Heinonen J, et al. Maternal antibiotic use during pregnancy and childhood obesity at age 5 years. Int J Obes (Lond). 2019;43(6):1202-1209. DOI: 10.1038/s41366-018-0316-6.