On December 2, PCORI will release the Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA) to support high-quality patient-centered comparative clinical effectiveness research (CER). Category 3 supports PCORnet® Studies that advance PCORI’s National Priorities for Health with direct costs of up to $12 million.
PCORnet® Studies are defined as those that:
- Include two or more PCORnet® Clinical Research Networks and performance metrics
- Exchange best practices with the network to promote continuous learning and improvement
- Demonstrate a commitment to stakeholder engagement and partnership
- Use PCORnet resources to improve the efficiency of patient-centered CER
PCORI has identified three specific areas of emphasis for this PFA: addressing obesity, treatments and strategies to address menopausal symptoms, and improving care delivery for individuals with intellectual and developmental disabilities (IDD).
Letters of Intent (LOI) are due January 6.
Are you ready to learn more and apply? Take these three steps to prepare:
- Contact the PCORnet® Front Door as soon as possible. All applicants submitting to the BPS Category 3 PFA are required to contact the PCORnet® Front Door prior to submitting their LOI. The PCORnet® Front Door can advise on study feasibility and costs associated with working with PCORnet, provide data to inform study design, offer best practices for stakeholder engagement, and more.
- Register for the December 8 PCORI Applicant Town Hall to learn more about this PFA and how to submit a responsive LOI and application.
- Check out this webinar for an overview of PCORnet and the specific requirements for the Category 3: PCORnet® Studies option in the BPS PFA.
On December 2, PCORI will also release a PFA on Improving Health Decision Making with Comparative Clinical Effectiveness Research: Retrospective Observational Studies Leveraging Existing Data Sources.
This PFA seeks out well-designed, retrospective observational studies using established data sources and infrastructure, such as resources available through PCORnet. Studies should compare existing interventions that are either currently in widespread use or represent a current decisional dilemma that has a robust body of evidence. This could include clinical interventions (such as medications or diagnostic tests) or delivery system interventions (such as workforce and healthcare service delivery designs).
Long-term comparative effectiveness and safety assessments (i.e., more than five years of post-intervention follow-up) and research looking at populations that are not as easily randomized are encouraged. Applications must address one of the PCORI topic themes:
- Improving Outcomes for People with Intellectual and Developmental Disabilities,
- Preventing Maternal Morbidity and Mortality,
- Improving Mental and Behavioral Health,
- Improving Metabolic and Endocrine Health,
- Managing Pain,
- Addressing Rare Diseases,
- Addressing Sensory Health,
- Addressing Substance Use.
There is a PCORI Applicant Town Hall about this funding opportunity on December 10. Learn more.
A PFA supporting Partnering Research and Community Organizations for Comparative Clinical Effectiveness Research Across the Cancer Care Continuum is also set to open on December 2, with an Applicant Town Hall on December 9. Learn more. LOIs for both opportunities are due January 6.
If you are interested in using PCORnet to power your next research effort, now is the time. Be on the lookout for more information from PCORI on December 2.