Featured In This Issue
Funding Opportunities: Share the Latest Funding Announcements with Your Network of Researchers
Research Results: New Published Insights from Studies Using PCORnet
- Learn How the PCORnet National Stakeholder Group Provides Strategic Insight
- Data from New Sites Are Now Available Via PCORnet for Research
- How the DHR Health Institute for Research and Development is Expanding the Breadth and Diversity of PCORnet Data Resources
- Two Updated Webpages Make Exploring Research Powered by PCORnet® Easier
- See Our Latest PCORnet® Study Tracker
- Public Query Data Report on Maternal Morbidity and Mortality Coming Soon
A National Health & Research Data Resource for Patient-Centered Comparative Clinical Effectiveness Research
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Past Issues
Please share new funding announcements with your network of researchers.
PCORI Releases Funding Announcement for Broad Pragmatic Studies
PCORI has released a Category 3 Broad Pragmatic Studies (BPS) funding announcement for researchers interested in using PCORnet® for patient-centered comparative clinical effectiveness research (CER). This BPS Category 3 funding opportunity supports PCORnet® Studies with direct costs up to $12 million. PCORnet® Studies use the Network to conduct observational studies and/or pragmatic trials that are national in scale. Category 3 PCORnet Studies® must include two or more PCORnet® Clinical Research Networks and share study progress, performance metrics, and best practices with the Network to promote continuous learning and improvement. PCORnet® Studies will leverage the PCORnet® Common Data Model as appropriate.
- Applicant Workshop
- Letter of Intent (LOI) Deadline, June 4, 2024; 5 pm (ET)
- Applicants must contact the PCORnet® Front Door prior to LOI submission.
- Application Deadline, Sept. 4, 2024; 5 pm (ET)
Other PCORI and NIH funding announcements to share with your colleagues include:
PCORI Rare Disease Research Funding: A new topical PCORI PFA seeks to fund high-quality patient-centered CER projects that focus on rare diseases.
- Application Deadline, Sept. 4, 2024; 5 pm (ET)
PCORI Phased Research Funding: This PCORI PFA invites applications for high-quality patient-centered CER projects that will address critical decisions faced by patients, families, caregivers, clinicians, and the health and healthcare community and for which there is insufficient evidence.
- Application Deadline, Sept. 4, 2024; 5 pm (ET)
PCORI Funding for Research that Improves CER Methods: With this PCORI PFA, PCORI aims to fund studies that address high-priority methodological gaps in patient-centered CER.
- Application Deadline, Sept. 4, 2024; 5 pm (ET)
NIH Funding for ‘Network Research Hubs’: This NIH opportunity invites organizations currently affiliated with and participating in specific existing clinical research networks (e.g., PCORnet) to serve as “Network Research Hubs” and establish the infrastructure to conduct clinical research in primary care settings.
- Application Deadline, June 14, 2024; 5 pm (ET)
The Latest Published Insights from Studies Using PCORnet
Check out the most recent publications from study teams using the PCORnet infrastructure.
- Limitations of Noninvasive Tests-Based Population-Level Risk Stratification Strategy for Nonalcoholic Fatty Liver Disease
- Making progress against rare cancers: A case study on neuroendocrine tumors
- Association between SARS-CoV-2 infection and select symptoms and conditions 31 to 150 days after testing among children and adults
Learn How the PCORnet National Stakeholder Group Provides Strategic Insight
The PCORnet National Stakeholder Group met in May to review recent progress of PCORnet over the past six months and to provide strategic guidance that supports PCORnet® Network Partners in their efforts to enable national-scale patient-centered comparative clinical effectiveness research (CER). The group’s members, who work to bridge an understanding of federal- and private-sector health data and research initiatives that are potentially relevant to PCORnet® Network Partners, left the meeting invigorated.
“Learning about the power of PCORnet has been eye-opening for me. There are so many ways this powerful infrastructure can be used to help research national priorities for health,” said Ricardo Rocha, head of Medical Affairs at Intellia Therapeutics. “I am particularly excited to see the growth in national-scale PCORnet® Studies that are answering questions critical to the work of companies like Intellia, as well as the broader research community.”
Data from New Sites Are Now Available Via PCORnet – Find Out How Can They Support Your Research
Last year, PCORI approved funding for the addition of 16 sites to expand the reach of the eight PCORnet® Clinical Research Networks (CRNs), and data from many of those new sites are now available via PCORnet.
“This expansion makes the Network’s breadth and depth even more robust, empowering PCORnet users to close more gaps in evidence than was previously possible,” said Betsy Shenkman, PCORnet Steering Committee Chair.
How the DHR Health Institute for Research and Development is Expanding the Breadth and Diversity of PCORnet Data Resources
Our “Meet the New Sites” series offers a deeper look at the new PCORnet sites, one at a time. First up is DHR Health Institute for Research and Development (part of the REACHnet CRN) in Edinburg, Texas.
There are many reasons we are excited about the addition of DHR Health as a site participating in the Network, but a big one is that it opens opportunities for more insights into people of Hispanic descent, who make up 19 percent of the U.S. population but less than 1 percent of U.S. clinical trial participation.
Two Updated Webpages Make Exploring Research Powered by PCORnet® Easier
PCORnet.org now includes two helpful new webpages. The new Research page shares expanded case studies exploring the kind of questions PCORnet can be used to answer, and the new Studies page allows visitors to search all PCORnet® Studies by Status, Population, therapeutic Area, or keyword. Check them out today.
See Our Latest PCORnet® Study Tracker
The PCORnet® Study Tracker demonstrates our commitment to transparency with regular updates around the quantity, funding amount, and therapeutic focus of all PCORnet® Studies. Our most recent report published in March reveals that 41 PCORnet® Studies are currently active across 14 therapeutic focus areas, with most funding dollars coming from federal grants.
Public Query Data Report on Maternal Morbidity and Mortality Coming Soon
Maternal morbidity and mortality research in the U.S. is important to help us understand disparities in health outcomes for pregnant women and new mothers. It can also help us identify risk factors for complications, improve clinical practices, and develop evidence-based policies to reduce preventable deaths during pregnancy, childbirth, and the postpartum period.
PCORnet® Clinical Research Networks are well-positioned to facilitate observational and clinical research to help answer these questions.
A recent query of the Network, covering five years, identified about 1.5 million deliveries of newborns across sites participating in PCORnet. The query assessed maternal race, ethnicity, and severe maternal morbidity, capturing 21 specific unexpected outcomes of labor and delivery as well as outcomes up to 30 days postpartum.
The detailed report will be available in the coming months, allowing researchers to understand how PCORnet can be used to power critical maternal morbidity and mortality insights to advance patient care.
Are you interested in learning what access to insights from encounters with more than 30 million people across the U.S. can offer your study? Reach out through the PCORnet® Front Door, the access point for all PCORnet resources.
PCORnet® is intended to improve the nation’s capacity to efficiently conduct patient-centered health research, particularly comparative clinical effectiveness research (CER), by providing a large, highly representative network of health data, research expertise, and patient insights. PCORnet® has been developed with funding from the Patient-Centered Outcomes Research Institute (PCORI®).